In recent years there has been increasing interest in the ability to perform measurements of not just the total concentration of elements in samples, but also the relative levels of the different species of elements that are present. This is because each molecular compound or oxidation state of an element exhibits unique properties such as toxicity, reactivity or metabolic pathway in living organisms. An effective analytical approach to enable this type of speciated elemental analysis is by separation, using a chromatographic technique, and detection using the highly sensitive element specific technique of ICP-MS. Separations for volatile species can be performed using gas chromatography (GC), whilst detection with high resolution ICP-MS offers the benefit of increased sensitivity and selectivity. The Thermo Scientific kit enables analysts working in the environmental, clinical and biological markets to detect and quantify the volatile compounds of elements such as sulfur, tin, phosphorous, mercury and bromine, at significantly lower levels than traditional techniques thanks to the solution’s high sensitivity and, in some cases, the ability to resolve interfering ions from the mass spectrum.
Thermo Fisher Scientific already offers a GC coupling kit for the Thermo Scientific XSERIES 2 quadrupole-based ICP-MS. and has used the same unique dual sample introduction for the high resolution ICP-MS. This offers simple instrument set up and internal standardization using simultaneously nebulized solutions in parallel to the GC sample gas stream. This new GC-ICP-MS interface for high-resolution ICP-MS is unique in the market.
The new Thermo Scientific coupling kit enables high resolution ICP-MS to work alongside any GC system, giving customers the ability to detect species using high resolution with their existing GC system.