Thermo Fisher Scientific Announces Three New Products for Easier, Faster Quantitative Proteomic Analysis

Proteomics researchers have largely shifted their focus from high-throughput protein identification to measuring protein expression changes via relative quantitation, which may give clues to the role those proteins play in disease, said Amy Zumwalt, proteomics marketing programs manager for life sciences mass spectrometry at Thermo Fisher Scientific.
With products like iSRM and Pinpoint, Thermo Fisher Scientific is leading the industry in providing high-performance, easy-to-use technology that functions in a single, seamless workflow for proteomics discovery.

iSRM and Pinpoint software enhance targeted protein quantitation One of the biggest challenges in proteomics quantitation is to simultaneously verify and quantify low-level biomarkers. iSRM, which is available on all Thermo Scientific TSQ (triple stage quadrupole) instruments, increases the sensitivity and selectivity of targeted quantitation assays for simultaneously verifying and quantifying targeted proteins.

With traditional SRM-based assays, the user always had to compromise between selectivity and sensitivity, said Andreas Huhmer, proteomics marketing director for life sciences mass spectrometry at Thermo Fisher Scientific. With iSRM, the instrument maintains high sensitivity and high selectivity. iSRM is designed to target as many as 1000 peptides and handle over 10,000 SRM transitions in a single experiment. These numbers are higher than past technologies could deliver. As such, iSRM has the potential to significantly decrease labor and cost per analysis by increasing the number of peptides targeted in a single analysis.

As part of this integrated targeted quantitation workflow, Thermo Fisher Scientific is also introducing Pinpoint software. Pinpoint, available as a free download, is designed to simplify the transition from early-stage biomarker discovery to larger-scale, quantitative verification of putative biomarkers and general quantitative proteomics (see www.thermo.com/pinpoint for details).

For more information about iSRM and Pinpoint software, please visit the Thermo Scientific hospitality suite at the Philadelphia Marriot Downtown in Salons G-K during ASMS 2009. For more information about Thermo Scientific mass spectrometry solutions, please call 1-800-532-4752, e-mail analyze@thermofisher.com or visit www.thermo.com/proteomics

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.

For a full list of all press releases announcing new products at ASMS 2009, please visit www.thermo.com/ASMS.

About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, enabling our customers to make the world healthier, cleaner and safer. With 2008 revenues of $10.5 billion, we have approximately 34,000 employees and serve over 350,000 customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as environmental and industrial process control settings. Serving customers through two premier brands, Thermo Scientific and Fisher Scientific, we help solve analytical challenges from routine testing to complex research and discovery. The Thermo Scientific brand represents a complete range of high-end analytical instruments as well as laboratory equipment, software, services, consumables and reagents to enable integrated laboratory workflow solutions. Fisher Scientific provides a complete portfolio of laboratory equipment, chemicals, supplies and services used in healthcare, scientific research, safety and education. Together, we offer the most convenient purchasing options to customers and continuously advance our technologies to accelerate the pace of scientific discovery, enhance value for customers and fuel growth for shareholders and employees alike. Visit www.thermofisher.com.

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